Pub No:
209
Title:
Binding of isocyanides to five-coordinate, durene-capped hemes
Authors:
David, S., James, B.R., and Dolphin D.
Journal:
Can. J. Chem.
Year:
1987
Pages:
65, 1098-1102
Abstract:
Solution data at 20 oC are presented for the binding of tert-butylisocyanide (tBuNC) and tosylmethylisocyanide (TMIC) to the 5-coordinate hemes Fe(porp)(Cy2Im), where Cy2Im = 1,5-dicyclohexylimidazole and porp = the dianion of some durene-capped porphyrins with variable length linking methylene straps on either side of the durene moiety (4/4, 5/5, or 7/7 methylenes). The tBuNC and TMIC ligands are used to probe the steric nature of the distal binding site under the cap, in particular the resp. central and peripheral effects as defined by T. G. Taylor et al. (1984). The binding constants range from 1.1 x 109 M-1 for the 7/7-TMIC system to immeasurably small for the 4/4-tBuNC system, this range spanning data reported in the literature for related anthracene- and adamantane-capped systems.

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