1-Bromo-19-Methylbiladienes-ac; Useful Precursors to Porphyrins
Wijesekera, T. and David Dolphin
The use of 1-bromo-19-methylbiladienes-ac in the synthesis of porphyrins is described. The stepwise construction of the linear tetrapyrrole via 5?-unsubstituted 5-methyldipyrromethenes and 5?-bromo -5-bromomethyldipyrromethenes as well as improvements and limitations in methodology are discussed. Several examples of its successful application are presented.