Pub No:
33
Title:
A Model for the Mechanism of Action of Coenzyme B12 Dependent Enzymes. Evidence for Rearrangements in Cobaloximes
Authors:
Silverman, R.B., David Dolphin, and Babior, B.M.
Journal:
J. Am. Chem. Soc.
Year:
1972
Pages:
94, 4028-4030
Abstract:
The product obtained from the methanolysis of 2-acetoxyethyl-2-14C-(pyridine)cobaloxime indicates that this rearrangement occurs via the intermediacy of a Co(III)-π complex. The hypothesis that the reactions catalyzed by coenzyme B 12-dependent enzymes proceed via similar rearrangements is discussed.

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